Athletics @ St. Louis Cardinals Player Props, Picks and Predictions - 9/3/2025 7:45 PM EDT

We have your Athletics @ St. Louis Cardinals prop betting and game preview needs covered as the Athletics hit the road to face the St. Louis Cardinals.

Athletics @ St. Louis Cardinals Pick

Best Moneyline Odds: Athletics -104 [Fanduel]
Best Spread Odds: Athletics +1.5 -180 [ESPN BET]
Best Total Odds: Under 8.5 +100 [ESPN BET]

Game Info

Date: 2025-09-03
Time: 7:45 PM EDT
Location: Busch Stadium, St. Louis
TV: -

Athletics @ St. Louis Cardinals Preview

The St. Louis Cardinals (69-71) are set to host the Oakland Athletics (64-76) in the third game of their series at Busch Stadium. The series is currently tied 1-1, with the Cardinals coming off a 2-1 home victory that snapped a two-game losing streak. The Cardinals have a 38-33 home record this season and are 71-61 in over/under bets. Their offense boasts a .247 batting average, .315 OBP, and .383 slugging percentage. Matthew Liberatore (6-11, 4.32 ERA, 1.32 WHIP) is the projected starting pitcher for the Cardinals. Liberatore's team is 12-11 against the spread in his starts, and they are 4-9 when he starts as the moneyline favorite. He has struggled at home with a 4.55 ERA and has allowed 3+ earned runs in his last four starts. Key offensive players for the Cardinals include Alec Burleson, who leads the team with 123 hits and a .286 batting average, and Willson Contreras, who leads in RBIs (74) and home runs (20). Nolan Arenado, Alec Burleson, Brendan Donovan, Yohel Pozo, John King, Zack Thompson, Drew Rom, and Cooper Hjerpe are all dealing with injuries for the Cardinals. The Athletics, despite their 64-76 record, have a decent 35-36 road record and are 71-63 in over/under bets. They are coming off a 1-2 road defeat to the Cardinals and have a 1-4 record in their last five games. Their offense has a .253 batting average, .319 OBP, and .433 slugging percentage. Jeffrey Springs (10-9, 4.17 ERA, 1.19 WHIP) is the projected starter for the Athletics. Springs has been more effective on the road with a 3.66 road ERA. The Athletics are 14-12 against the spread in Springs' starts and have an 11-6 record when he starts as the moneyline underdog. Brent Rooker leads the Athletics with 146 hits, while Jacob Wilson is their best hitter with a .315 batting average. Shea Langeliers leads the team with 29 home runs, and Tyler Soderstrom has a team-high 81 RBIs. The Athletics are dealing with several injuries, including Jack Perkins, Denzel Clarke, Max Muncy, Luis Medina, Grant Holman, and José Leclerc.

Historic Head-to-Head Stats and Analysis

The Cardinals hold a slight edge in recent head-to-head meetings, with a 5-3 record in their last eight matchups against the Athletics. In games played in St. Louis, both teams are tied with 3 wins each in their last six meetings. The most recent game on September 2, 2025, saw the Cardinals win 2-1. In 2025, the Athletics and Cardinals are tied 1-1 in their head-to-head games. The "Under" has been a prevalent trend in their recent encounters, hitting in five of their last seven meetings. The Athletics have shown resilience as road underdogs, winning each of their last six games in that scenario following a loss.

Pick: Athletics Moneyline (-104)

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While the Cardinals are slight home favorites, the Athletics present a compelling case for an upset. Jeffrey Springs, the Athletics' starting pitcher, has demonstrated better performance on the road with a 3.66 ERA, which is a significant factor in this matchup. Conversely, Cardinals' starter Matthew Liberatore has struggled at home, carrying a 4.55 ERA and allowing three or more earned runs in his last four starts. This pitching disparity, especially with Springs' road form and Liberatore's home struggles, gives the Athletics a distinct advantage. Furthermore, the Athletics have a strong trend of winning as road underdogs after a loss, which aligns with their current situation. Considering these factors, backing the Athletics on the moneyline offers good value.

Top Player Prop Picks

Iván Herrera Over 0.5 Hits (-260)

Iván Herrera has been a consistent hitter for the Cardinals, especially recently. He has hit the over on his hits prop in 100% of his last 5 games and 90% of his last 10 games. His season average is 1.02 hits per game, and he has hit the over in 69.77% of his games this season. In his limited exposure to the Athletics in 2025, he has hit the over in 100% of his two appearances, averaging 1.0 hit. Given his strong recent form and historical performance against the Athletics, taking the over on his hits prop at [Fanduel](https://ui.sharpsports.io/place/MRKT_ebe4fabb308945c9bde01316a5b24b63/BOOK_Rf7xRhS7TKQUl94Xkt5w?line=0.5) is a solid play.

Nick Kurtz Over 0.5 Walks (+110)

Nick Kurtz has shown a strong ability to draw walks recently. He has hit the over on his walks prop in 80% of his last 5 games and 80% of his last 10 games. His average walks per game over his last 5 games is 0.8, and 0.9 over his last 10 games. While his season average is 0.57 walks per game, his recent trend indicates an increased plate discipline. He also hit the over in his only appearance against the Cardinals in 2025, drawing 1 walk. With plus odds available, the over on Nick Kurtz's walks prop at [DraftKings](https://ui.sharpsports.io/place/MRKT_cc4cbbca3fdf4526bef5e9059254dcfe/BOOK_nhLZ9l5DRs6w6KcE2n7vnw?line=0.5) is an attractive option.

Thomas Saggese Over 1.5 Hits + Runs + RBIs (+110)

Thomas Saggese has been performing well in the combined Hits + Runs + RBIs category. He has hit the over in 100% of his last 5 games, averaging 2.4 H+R+RBI. Over his last 10 games, he has hit the over 70% of the time, with an average of 1.7. In his single appearance against the Athletics in 2025, he hit the over, recording 2.0 H+R+RBI. Despite a lower season hit rate for this prop, his recent surge in production makes the over on Thomas Saggese's Hits + Runs + RBIs prop at [DraftKings](https://ui.sharpsports.io/place/MRKT_235f84746b35499ba7e331f6b5f23c86/BOOK_nhLZ9l5DRs6w6KcE2n7vnw?line=1.5) a favorable bet.