Here is the Pickwatch BetSmart Preview for the Boston Red Sox vs. New York Yankees in Game 2 of the AL Wild Card Round in the 2025 MLB Playoffs.

Boston Red Sox vs. New York Yankees Game Info

Date: Wednesday, October 1, 2025
Time: 6:08 p.m. ET
Location: Yankee Stadium — Bronx, New York
TV: ESPN

Red Sox vs. Yankees Betting Info

Spread / Run Line
- Red Sox +1.5 (-142)
- Yankees -1.5 (+118)
Moneyline
- Red Sox +154
- Yankees -184
Total (Over/Under)
- Over 7.5 (-105)
- Under 7.5 (-115)

*Odds via FanDuel

Season Betting Trends

Moneyline
- Red Sox: 90-73
- Yankees: 94-69
Run Line
- Red Sox: 83-80
- Yankees: 78-85
Totals (Over-Under)
- Red Sox: 77-82-4
- Yankees: 76-81-6

Boston Red Sox (90–73) @ New York Yankees (94–69) Preview

Boston stunned New York in Game 1, winning 3–1 behind strong pitching and clutch hitting, putting the Yankees on the brink of elimination. Now, New York must win at home to force a Game 3 and keep its postseason alive.

Analysts expect the Yankees to tap Carlos Rodón (18-9, ~3.09 ERA) to bounce back, while Boston goes with Brayan Bello (11-9, ~3.35 ERA) aiming to close it out.

The Yankees lineup will be retooled slightly, with players like Trent Grisham returning to the leadoff spot, Jazz Chisholm Jr. and Ben Rice and others adjusting to face Bello’s stuff. On the Boston side, their bullpen—already well-rested—will be leaned on if Rodón gives them a chance.

The market leans heavily on New York given the desperation factor, home field, and pitching matchups, but Boston’s regular-season dominance over New York (9–4 record) gives them legitimate hope.

Head-to-Head Stats and Analysis

The New York Yankees Cubs lead the all-time series 1,261–1,050–14 against the Boston Red Sox. Here are the last 5 matchups:

Red Sox 3, Yankees 1 — September 30, 2025
Red Sox 6, Yankees 4 — September 14, 2025
Red Sox 12, Yankees 1 — August 23, 2025
Yankees 7, Red Sox 2 — August 24, 2025
Red Sox 11, Yankees 7 — June 8, 2025

BetSmart Betting Rundown

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Arbitrage

Our Arbitrage Betting Tool is currently not identifying any arbitrage betting opportunities for guaranteed profit. The tool scans all major sportsbooks in real-time, though, so be sure to check back often as odds and lines change often, and an arbitrage opportunity could still become available before the first pitch.

Middles

Our Middle Betting Tool is currently not identifying any middle betting opportunities. The tool scans all major sportsbooks in real-time, though, so be sure to check back often as odds and lines change often, and a middle bet opportunity could still become available before the first pitch.

Positive EV

Our Positive EV Betting Tool has identified 1 positive expected value wager, and provided data on the expected value percentrage, suggested Kelly Stake, and how often the bet has hit in the last 5, 10 and 15 games.

Player Props

Our Prop Finder Tool has identified over 200 different player prop bets, and provided data on how often each player has hit the specific prop in the last 5, 10 and 15 games.

Red Sox vs. Yankees: Expert Picks

Visit our Expert Picks page to view picks and data from experts to see where the consensus is on the Red Sox vs. Yankees moneyline, run line and total.