Here is the Pickwatch BetSmart Preview for the Minnesota Vikings vs. Los Angeles Chargers game in Week 8 of the 2025 NFL Season.

Minnesota Vikings vs. Los Angeles Chargers Game Info

Date: Thursday, October 23, 2025
Time: 8:15 PM ET
Location: SoFi Stadium — Inglewood, California
TV: Amazon Prime Video

Vikings vs. Chargers Betting Odds

Point Spread
- Vikings +3.5
- Chargers -3.5
Moneyline
- Vikings +155
- Chargers -170
Total
- Over 44.5
- Under 44.5

Season Betting Records

Moneyline
- Vikings: 3-3
- Chargers: 4-3
Against the Spread
- Vikings: 3-3
- Chargers: 2-4-1
Totals (Over-Under)
- Vikings: 5-1
- Chargers: 3-4

Minnesota Vikings (3–3) @ Los Angeles Chargers (4–3) Preview

Minnesota heads west on short rest after their Week 7 loss, aiming to halt a slide and regain offensive rhythm. The Vikings face significant disruption up front, with both starting tackles – Christian Darrisaw and Brian O’Neill – listed as questionable, while QB J.J. McCarthy (ankle) and RB Aaron Jones (hamstring) are also hampered.

Their opponent, the Chargers, is in a bit of a rebound mode after dropping three of four, and they’re looking to get back on track behind QB Justin Herbert, who continues to pile up passing yards despite increased sack vulnerability. The Chargers’ offensive line remains a concern, with LT Joe Alt and RT Trey Pipkins listed questionable.

On the defensive side, L.A. wants to reclaim identity after giving up explosive plays. Minnesota’s offense—featuring WR Justin Jefferson, WR Jordan Addison and TE T.J. Hockenson—poses a multi-headed challenge. Jefferson in particular has dominated this matchup historically and will be a major target in the passing game.

Given the injury instability for both teams, this game may hinge on turnovers, sacks, and field position more than scoring explosiveness. Los Angeles has home-field and a slight edge in continuity, but the Vikings’ playmaker-heavy offense is no easy matchup. Expect the Chargers to be favored, but the spread and total may reflect vulnerable lines on both sides.

Vikings/Chargers Head-to-Head (H2H) Stats and Analysis

Minnesota Vikings lead the all-time series 8-7 vs. the Los Angeles Chargers. Here's their last 5 games:

Los Angeles Chargers 28, Minnesota Vikings 24 — September 24, 2023
Minnesota Vikings 27, Los Angeles Chargers 20 — November 14, 2021
Minnesota Vikings 39, Los Angeles Chargers 10 — December 15, 2019
Minnesota Vikings 31, San Diego Chargers 14 — September 27, 2015
San Diego Chargers 24, Minnesota Vikings 17 — September 11, 2011

BetSmart Betting Rundown

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NOTE: All available bets are as of time of publication. Odds and lines change often, so be sure to check each subsequent Pickwatch betting tool for the latest numbers.

Arbitrage

Our Arbitrage Betting Tool is currently identifying 3 arbitrage betting opportunities for guaranteed profit.

Middles

Our Middle Betting Tool is currently identifying 49 middle betting opportunities.

Positive EV

Our Positive EV Betting Tool is currently identifying 17 different positive expected value wagers, and provided data on the expected value percentrage, suggested Kelly Stake, and how often the bet has hit in the last 5, 10 and 15 games.

Player Props

Our Prop Finder Tool is currently identifying over 200 different player prop bets, and provided data on how often each player has hit the specific prop in the last 5, 10 and 15 games.

Vikings vs. Chargers: Expert Picks

Visit our Expert Picks page to view picks and data from over 200 experts to see where the consensus is on the Vikings vs. Chargers moneyline, point spread and total points.