Oregon Ducks @ Northwestern Wildcats Player Props, Picks and Predictions - 9/13/2025 12:00 PM EDT

We have your Oregon Ducks @ Northwestern Wildcats prop betting and game preview needs covered as the Oregon Ducks hit the road to face the Northwestern Wildcats.

Oregon Ducks @ Northwestern Wildcats Pick

Best Moneyline Odds: Oregon Ducks -6000 (ESPN BET), Northwestern Wildcats +2200 (Fanduel).
Best Spread Odds: Oregon Ducks -27.5 (-112) (BetRivers), Northwestern Wildcats +28.0 (-110) (Caesars).
Best Total Odds: Over 51.5 (+100) (ESPN BET), Under 51.5 (+100) (Caesars).

Game Info

Date: 2025-09-13
Time: 12:00 PM EDT
Location: Lanny and Sharon Martin Stadium, Illinois
TV: -

Oregon Ducks @ Northwestern Wildcats Preview

The Oregon Ducks, currently ranked No. 4 in the AP Poll and No. 1 in ESPN's Football Power Index (FPI), are set to hit the road for their first away game of the 2025 season. They enter this matchup against the Northwestern Wildcats with an impressive 2-0 record, having dominated their first two opponents. The Ducks routed Montana State 59-13 and followed that with a massive 69-3 victory over Oklahoma State, showcasing an explosive offense and a stifling defense. Quarterback Dante Moore has been a standout, delivering a near-perfect performance against Oklahoma State with 16-of-21 passing for 266 yards and three touchdowns. The Ducks' rushing attack has also been formidable, accumulating 312 total yards and five touchdowns in their last outing, highlighting their depth at the position. Defensively, Oregon has been equally impressive, limiting opponents and forcing turnovers, including two pick-sixes against Oklahoma State.

The Northwestern Wildcats come into this game with a 1-1 record. After a challenging season opener against Tulane, they bounced back with a decisive 42-7 win over FCS Western Illinois. Quarterback Preston Stone showed improvement in Week 2, completing 21 of 29 passes for 245 yards and three touchdowns, and the Wildcats demonstrated a strong ground game with 281 rushing yards. However, Northwestern is generally rated as a below-average team nationally, and this game presents a significant step up in competition. While the early 9 AM PT kickoff time for the Ducks could be a factor, Oregon's recent performances suggest they are well-prepared to maintain their high level of play regardless of the circumstances.

Historic Head-to-Head Stats and Analysis

The Oregon Ducks and Northwestern Wildcats have a limited head-to-head history. Records indicate that Saturday's contest will be just the second meeting between these two programs since at least 974. In their only previous recorded encounter, the Oregon Ducks lost to the Northwestern Wildcats with a score of 14-10. That game was played in Evanston on October 5th.

Pick: Oregon Ducks -27.5 Spread

The Oregon Ducks have been nothing short of dominant in their first two games, not only winning convincingly but also easily covering substantial spreads. Their offense is firing on all cylinders, led by the impressive play of quarterback Dante Moore and a deep, effective rushing attack. On the defensive side, Oregon has proven to be suffocating, limiting opponents' scoring opportunities and forcing turnovers. While the Northwestern Wildcats showed some signs of life against an FCS opponent in Week 2, their struggles against Tulane in the season opener highlight the significant talent and performance gap between them and a top-tier team like Oregon. Despite this being Oregon's first road game of the season and an early kickoff for the Ducks, their overwhelming offensive firepower and defensive prowess make them a strong pick to cover this large spread and continue their dominant start to the season.

Top Player Prop Picks

Please note: Specific player prop lines and odds were not available in the provided research. The following are narrative-based predictions for potential player performance.

Dante Moore (Oregon Ducks) - Passing Touchdowns

Oregon's quarterback Dante Moore has been in stellar form, showcasing his five-star talent in the Ducks' opening games. Against Oklahoma State, he was highly efficient, completing 16 of 21 passes for 266 yards and three touchdowns. Given Oregon's high-octane offense and their tendency to put up big numbers, especially against less formidable defenses, Moore is poised for another multi-touchdown performance. His ability to distribute the ball and the Ducks' array of offensive weapons suggest he will be a central figure in their scoring efforts.

Noah Whittington (Oregon Ducks) - Rushing Yards

Noah Whittington has established himself as a key component of Oregon's potent rushing attack. He leads the team with 159 rushing yards and two touchdowns through the first two weeks, including a 91-yard performance against Oklahoma State that featured a 59-yard touchdown run. The Ducks have demonstrated exceptional depth in their backfield, accumulating over 300 rushing yards in their last game. Whittington's role as the primary ball-carrier, combined with Oregon's offensive line, positions him to gain significant yardage against the Northwestern defense.

Preston Stone (Northwestern Wildcats) - Passing Yards

Northwestern quarterback Preston Stone showed considerable improvement in Week 2, throwing for 245 yards and three touchdowns against Western Illinois. As the Wildcats face a highly-ranked Oregon team, they will likely need to rely heavily on Stone's arm to move the ball and keep pace, particularly if they fall behind early. This scenario could lead to a higher volume of passing attempts for Stone, providing him with opportunities to accumulate passing yards as Northwestern attempts to generate offense against a strong Ducks defense.